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doi:10.3390/s120912741

Second, while this study proposes a mechanistic hypothesis based on proteomic findings, future studies using immunohistochemistry and cellular co-localization are needed to identify the cellular sources of CINC-3 and CNTF expression and clarify DPs cellular targets.Thirdly, this study is the absence of behavioral assessments such as von Frey test, weight bearing, or gait analysis, future studies will incorporate these approaches to further investigate the functional implications of the molecular changes observed

Sample sizes for each animal study were estimated based on preliminary data or previous experience with these models predicting variance within each group

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