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Resveratrol protects against methotrexate-induced hepatic injury in rats

doi: 10.1055/s-2000-13206 110 ZhangQJiangYDengCWangJ

Changes in the kinetic mechanism: depending on whether the concentration of drug is in the therapeutic or overdose range

Peterson and Spence, 1998

[80]., showed various ill effects of prolonged use of various common antifungal drugs which included disorders like gastrointestinal, heart, lymphatic and many more

The GAA repeat sequence has been reported to bind to splicing factors such as those in the serine/arginine (SR)-rich protein family, and the proteins heterogeneous nuclear ribonucleoprotein (hnRNP) A1 and hnRNP A2, thereby rendering them incapable of splicing the introns during RNA processing ( FXN transcript, hence affecting the expression of the frataxin protein