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Batch-to-batch variation within the same pharmacy Even from the same pharmacy, consecutive vials might show slight color differences

non-phosphorylatable-VadK ( vadK:vadK His422Ala ) or phosphomimetic-VadK ( vadK:vadK His422Asp ) or a disrupted ATP-binding site, vadK:vadK Arg106Lys (predicted from (Ye et al, 2001) to disrupt ATP binding) and compared these strains to WT and with vadK:vadK (Basu et al, 2018)

They deliver a high dose of B12 directly into the muscle (intramuscularly) or under the skin (subcutaneously)

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