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10.1136/bmj.i4919 [DOI] [PMC free article] [PubMed] [Google Scholar] Sterne J

Optimization of the synthetic routes resulted in substantial improvement in the yields, as DYn-1 was synthesized in 2 steps (85% overall yield) and DYn-2 was synthesized in one step (96% yield)

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After treatment with GLY, the levels of GPX4, Nrf2 and HO-1 were significantly increased, while the protein level of HMGB1 in the model group was significantly decreased

Cardiovascular Risk, Organ Damage & Stroke Vasan RS, Song RJ, Xanthakis V, et al

The Bcl-2 family proteins regulate apoptosis by altering mitochondrial membrane permeabilization which leads to the release of apoptogenic factors such as cytochrome c , procaspases, and apoptosis inducing factor (AIF)