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The trial enrolled 281 participants across 42 research and healthcare centers in the United States, randomized to once-weekly subcutaneous retatrutide (0.5, 4, 8, or 12 mg), once-weekly subcutaneous dulaglutide 1.5 mg (active comparator), or placebo, over a 36-week treatment period

Common reasons include cracks in the filling, cracks in the tooth, decay under or around the filling, poor fit, persistent sensitivity, repeated food trapping or a rough surface that cannot be polished safely

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Improved blood flow enhances oxygen and nutrient delivery, which is essential for sustaining active growth during the anagen phase