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As of 2025, AOD-9604 should be regarded as a discontinued research peptide, not a therapeutic agent , with ongoing relevance confined to academic and mechanistic exploration

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Current evidence suggests that high-dose B12 supplementation can trigger acne in susceptible people by altering skin bacteria behaviour, though this does not affect everyone

To the Author or anyone else that has a reference for this statement?: The exception to this rule is the single preparation of the sub-Q or IM dose that exceeds the volume safely injected at a single site

Some clients experience mild, temporary soreness at the injection site

visceral fat fell about 40%. After withdrawal, insulin resistance returned in proportion to regained weight. Maintaining some weight loss did not preserve the full metabolic benefit when substantial regain occurred