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Chen C, Li X, Lv Y, et al

Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities

Similarly, in lung fibrosis, inhibition of the Nrf2 pathway is closely associated with elevated levels of oxidative stress in fibrotic tissues, which in turn triggers the abnormal deposition of fibrous components such as collagen, leading to a post-ferroptotic state in lung tissue cells [8, 9]

Further, the products of the GGT reaction may themselves lead to an increased free radical production

There are no safe oral (systemic) ways to reduce pigment in normal skin in patients with vitiligo