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PLoS One 2015;10(12):e0141641

(PubMed) Hoen WP, Lijmer JG, Duran M, Wanders RJ, van Beveren NJ, de Haan L

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Other factors implicated in early development of mDA neurons include Wnt1, En1, En2, Nurr1, Pitx3, Lmx1B, Foxa2, and Pax5 (Maxwell and Li, 2005)

Cell 96:857868 Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

This results in defective complexes I and II, which in turn diminishes the potential transfer of electrons in the respiratory chain, leading to an increase in ROS