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The inclusion of participants experiencing these hormonal changes may be another limitation of the study

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They block specific cytokines (TNF-alpha, IL-17, IL-23) with high precision

2017 Mar 23;169(1):3-5

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The increase in NAD+ levels activates pro-longevity factors such as sirtuins and AMPK, while inhibiting pathways like mTOR-S6K that negatively affect healthspan