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ERT attenuated oxidative stress and attenuated the structural and transcriptional changes in GLA-mutant human iPSC kidney organoids ERT is a major therapeutic option for patients with Fabry disease that improves Fabry-related symptoms and slows renal damage when started at a relatively early stage 11,12

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Can medicinal plants and bioactive compounds combat lipid peroxidation product 4-HNE-induced deleterious effects

in Manganese and Its Role in Biological Processes (Sigel, A., Freisinger, E

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Results and Discussion Chemical design of N -alkylpyridinium reagents We used the commercially available ( E )-3-(pyridin-4-yl)acrylic acid bearing a conjugated double bond, a carboxylic acid and a pyridine, to design a class of trifunctional reagents for site-selective dual modification