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10.1016/S0959-440X(02)00399-8 Curr

The affective aspect of pain is still not well-addressed, so there is a strong need to study the affective component of pain in animal models [182]

For contaminants with a poor toxicological database, e.g

Patients with untreated rosacea, active acne, or other inflammatory skin conditions often see slower results because the inflammatory environment is counteracting the remodeling signal