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All authors have made a significant contribution to this study and have approved the final manuscript

Reactive oxygen species (ROS) are natural products of mitochondrial oxidative metabolism and oxidative protein folding

Further testing beyond simple urinalysis to exclude the presence of heme is typically unnecessary

DSIP peptide vs

10.1182/blood-2017-11-737411 146

H296 ECL2 adopts a distinct rotamer in Cagri-bound CTR relative to Cagri-bound-AMY 1 R to accommodate the Glu linker that extends proximal to the top segment of TM5