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Therapeutic strategies targeting the iron-energy metabolism axis Development and application of iron chelators Given the crucial role of iron overload in AD pathogenesis, utilizing metal chelators to reduce excess iron in specific brain regions has garnered attention as a strategy to alleviate or even treat the disease

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Reducing gut microbiota-dependent TMAO production may be a potential strategy for the treatment of DN

Copper peptides like GHK-Cu are the most interesting to me from a regenerative standpoint, said Gould

Acknowledgments All authors would like to acknowledge the patients and normal individuals who contributed to this research work: we also acknowledge Hospital staff (Pakistan institute of medical sciences Islamabad (PIMS) for their cooperation