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Peer review Peer review information Nature Aging thanks Qingling Yang, Lindsay Wu, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Doses are always reviewed by a physician high-dose vitamin C in particular requires screening for conditions such as G6PD deficiency and certain kidney conditions before infusion

Other studies investigating the benefits of exercise for CIPN management are often inconsistent and report both improvement, or lack of positive effects of exercise on CIPN symptoms (Fernandes and Kumar, 2016

L-Carnitine and Acetyl L-Carnitine are two different forms of the same molecule, Carnitine, an amino acid naturally synthesised by the human body and plays an important role in cellular energy metabolism

Add the cost of regular bloodwork (comprehensive panels every 2 to 4 weeks initially), body composition scans, and any medical consultation, and the total monthly investment becomes substantial

No sponsor has funded that study