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Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity

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doi:10.1038/nature02317 Onoue S, Tsuda Y (2006) Analytical studies on the prediction of photosensitive/phototoxic potential of pharmaceutical substances