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RobinsonMGraySRWatsonMSKennedyGHillABelchJJFet al

and 3) gut epithelial cells (enterocytes) and stromal cells, responsible for detecting invading bacteria through extracellular and intracellular pattern recognition receptors (Toll-like receptors TLRs and NOD-like receptors-NLRs)

It biochemically represents various signaling pathways, such as kinase-mediated necroptosis, gasdermin-mediated necrosis downstream of inflammasomes, and an iron-catalyzed mechanism (14, 19, 20)