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McConnell et al., 2023) serve as vital immune barriers within the liver, safeguarding against foreign body recognition, phagocytosis, and degradation

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Oxygen therapy should be used cautiously, as higher oxygen concentrations enhance paraquat-induced oxidative injury and are recommended only in the presence of significant hypoxia

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These findings collectively underscore the broad therapeutic potential of targeting the Nrf2 system within astrocytes to mitigate oxidative damage and ferroptosis in PD