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Description

In the next section, we review the similarities and differences among the components of glutamatergic transmission in neurons and astrocytes

We each present a peer-reviewed scientific paper chosen because it contains novel, interesting, and actionable data

Published data document the pharmacokinetic orders of magnitude observed in humans: dose-dependent plasma Cmax, half-life of 5 to 6 hours when complexed with IGFBP-3/ALS, generally satisfactory tolerance with glycemic monitoring (hypoglycemic risk) and ophthalmological surveillance (rare papilledema)