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doi: 10.1513/AnnalsATS.201511-740PS 6 MonteagudoMRodriguez-BlancoTBarrechegurenMSimonetPMiravitllesM

Notably, a phase I clinical trial of the MCT1 inhibitor AZD3965 for advanced solid tumors (NCT01791595) has been completed, laying the groundwork for future clinical development

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Noguchi R, Nakayama K, Itoh M, Kamohara K, Furukawa K, Oyama JI, Node K, Morita S (2016) Development of a three-dimensional pre-vascularized scaffold-free contractile cardiac patch for treating heart disease

[DOI] [PubMed] [Google Scholar] 560.Li N., Tan S., Wang Y., Deng J., Wang N., Zhu S., Tian W., Xu J., Wang Q

Fc-containing fusion protein drugs predominantly target receptor-ligand interaction by acting as either antagonists to block receptor binding or agonists to directly stimulate receptor function, thereby reducing or increasing immune activity, respectively 11