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Drug Interactions: A Largely Unmapped Territory BPC-157 has documented pharmacodynamic interactions with at least the following drug classes in animal models: NSAIDs (it modulates COX-mediated prostaglandin pathways), corticosteroids (it has counter-regulatory effects on glucocorticoid-induced tissue atrophy), SSRIs and SNRIs (via serotonin system crosstalk), and anticoagulants (via platelet and NO pathway effects)

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Injuries to nerves and blood vessels (Small, 2004)

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Although TRPC1 alone functions as a SOCE in human adult retinal pigment epithelial-19 (ARPE-19) cells (Bollimuntha et al., 2005), TRPC3 and 4 only function as SOCE when co-expressed with TRPC1 (de Souza and Ambudkar, 2014)