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Cerebral ischemia is a common cause of death of hippocampal neurons, stroke, and fatality

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The circulating molar ratio of IGF-1 to IGFBP-3, indicating unbound and bioavailable circulating IGF-1, is significantly increased [126]

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These cells display intricate arborization patterns and form extensive gap junction-coupled networks that dynamically regulate synaptic activity, pH balance, and cerebral microcirculation