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The review also noted that GHK-Cus copper complexation ability raises Cu2+ penetration rates across the stratum corneum, and documented the development of formulation innovations including the TriHex peptide system that combine GHK-Cu-type tripeptides with hexapeptides to produce synergistic upregulation of regenerative genes and suppression of aberrant collagen deposition

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The procedure involved excising the skin and underlying cutaneous trunci muscle using a no

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10.1074/jbc.273.42.27499 43 CorradiV.BukiyaA