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Smoking from age 10 tied to heart damage by mid 20s Effects of Smoking Successive Low and High Nicotine Cigarettes on HypothalamicPituitaryAdrenal Axis Hormones and Mood in Men Neuropsychopharmacology Inhaled nicotine equivalent to cigarette smoking disrupts systemic and uterine hemodynamics and induces cardiac arrhythmia in pregnant rats Scientific Reports For smokers, fatal heart attack or stroke may be first sign of cardiovascular disease American Heart Association Smoking and High Blood Pressure American Heart Association Heart Failure: E Cigarettes Can Increase Risk By 21%

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