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Description

Macrophage-derived lncRNAs may change the landscape of cancer testing, diagnosis, and drug development, as our understanding of them expands, giving it a new way to control immunity and introduce new forms of cancer therapy

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In experimental settings, adenoviral Ad-K5cre (Keratin K5 regulated cre recombinase) infection of NMRI-Foxn1 nu/nu immunodeficient young mice resulted in the malignant transformation of basal cells into SCLC [185]