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The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway, Mol

Key Research Properties: Small molecule NNMT (nicotinamide N-methyltransferase) inhibitor Modulates NAD+ metabolism and methylation capacity Studied in context of energy expenditure and metabolic regulation NNMT is upregulated in obesity

Neuropsychopharmacology 36, 11711177

comprehensive inflammation modulation via cytokine regulation and NF-B pathway effects

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NMDA Receptor Modulation In brain research models, DSIPs effects appear to be at least partly mediated via NMDA receptors a glutamatergic ionotropic receptor family central to synaptic plasticity, learning and memory, and excitatory neurotransmission