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M., Rosenfeldt, M., Schmitz, W., Jiang, M., Saunders, B., Howell, M., Downward, J., Felsher, D

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In tumor cells, MYC-driven glutamine metabolism promotes tumor growth, drug resistance and immune escape [48], whereas MYC-regulated glutamine metabolism in immune cells supports the activation, proliferation and cytokine secretion of effector T cells and NK cells and enhances the immune response and other immune functions [49]