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Moreover, it can also restrain ferroptosis in chondrocytes, thus delaying the progression of osteoarthritis

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L-serine in serum is recognized by the TsR bacterial chemoreceptor, attracting Enterobacteriaceae and enables them to provide a competitive advantage for migration into enterohaemorrhagic lesions 139 (Fig

L., Lasker J

GSH acts as a direct scavenger of ROS and RNS and as a cofactor for GPx, which catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively

Almost 40% of the explainable variance of the full model (set to 100%) was contributed by serum metabolomic variables, with biological, dietary and microbiota taxonomic variables adding 5.5%, 4%, and 3.4%, respectively, independently explained variance (Fig