c perfringens has lipase Colonies of Clostridium on blood agar, surrounded by two Lipase & Lecithinase enzymes produced

What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology

PMID 29866424

So grab your sunglasses and dive into this illuminating topic together

In our pilot study of seven patients, we injected skin affected with vitiligo intra-dermally with a complex of vitamins and minerals and assessed the outcome

Their color may be identical to the surrounding skin or differ from it (varying from pink or red to light or dark brown)

Neuroradiol J