l glutathione pregnancy L-Glutathione 500 mg Antioxidants in Pregnancy: Do We

Mechanistic studies have revealed that altered expression of iron metabolism-related proteins (including GPX4, FTH1, TfR1, and HO-1), accumulation of lipid peroxidation products, and disruption of antioxidant defense systems (particularly the Nrf2/GPX4 pathway) are central to ferroptosis progression in cardiac tissue

(PubMed) Cardoso BR, Braat S, Graham RM

Biomed Pharmacother 115:108783 Mahmoud HS, Almallah AA, El-Hak HNG, Aldayel TS, Abdelrazek HM, Khaled HE (2021) The effect of dietary supplementation with Nigella sativa (black seeds) mediates immunological function in male Wistar rats

Wai CYY, Leung NYH, Leung ASY, Shum Y, Leung PSC, Chu KH et al (2021) Cell-based functional IgE assays are superior to conventional allergy tests for shrimp allergy diagnosis

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Since GSH depletion has been shown to promote ferroptosis, we examined the effects of knocking down TXND12 on ferroptosis in PAAD cells, and the results showed that knocking down TXNDC12 increased the levels of ROS, MDA, and decreased the expression of GPX4 (Fig