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Link Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D

Deficiency in vitamin B12 may cause anemia, fatigue, muscle weakness, intestinal problems, nerve damage, and mood disturbances

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For the purpose of this review, separate MMRM analyses were performed for the three phase 3a SCALE trials [38] and, in general, the treatment effects estimated using the MMRM analysis method were larger than those estimated using LOCF (Table 2)