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The link between BRCA1 and BRCA2 mutations and NRF2 regulation lies in the increased oxidative stress caused by defective DNA repair mechanisms (115)

The conversion of tyrosine into methoxy tyrosine and dimercaprol into methylated form are examples of O-methylation and S-methylation respectively (Figure 17)

This amine functionalization enhanced hydrophilicity, surface charge balance, and nanochannel size, resulting in a fourfold increase in water permeance and over 96% selective dye removal through pH-responsive electrostatic interactions