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Apoptotic assay To analyze cell apoptosis, the cells were incubated with 6 mM Cell Event Caspase-3/7 Green Detection Reagent (Life Technologies) for 30 min, then fixed and labeled with DAPI to counterstain nuclei

151,152 The mechanism of IAPP-induced cell death may also include inflammation and oxidative stress

The conjugation reactions transfer functional groups (e.g., glucuronic acid, sulfate, methyl, acetyl) from endogenous molecules to the drug or metabolite, resulting in the formation of highly polar and water-soluble conjugates

Storage and Handling Information Ipamorelin should be stored according to the product specification, with -20C used as the primary reference from the PeptideLabs catalog data

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