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Doses above 3 mg per day lack additional evidence of benefit and are not generally recommended

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However, certain skincare products may increase irritation when used together: Retinoids (Tretinoin, Adapalene) May increase skin sensitivity

The complex also exhibits redox-regulating and antioxidant activity, suppressing free radicalmediated damage while broadly impacting gene expression patterns linked to regeneration and cellular protection

A study of collagen production determined by studying skin biopsy samples using immunohistological techniques found that after applying creams to the thighs for one month, GHK-peptides had a significant effect on collagen production