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A study in healthy volunteers reported that a single injection of ipamorelin, at a dose of 100mcg/kg of body weight, led to dramatically increased GH levels that reached up to 80mIU/l (about 26.6ng/ml)

Furthermore, an exploratory analysis from the HOMAGE trial using targeted proteomics has found evidence of the spironolactone exerting pleiotropic effects across multiple mechanistic pathways in humans, spanning the mitigation of fibrosis, thrombosis, fluid congestion, vascular function, and inflammation [40]

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In comparison, studies have shown that Ipamorelin is highly selective and the only hormone it increases is HGH

For Ipamorelin, research protocols commonly reference doses in the range of 100-300mcg per administration, often administered one to three times daily depending on the research design