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For RNA extraction TRIzol reagent (Invitrogen, 15596026) was used according to the manufacturers instructions

The investigators used proportional hazards models to estimate the multivariable-adjusted hazard ratios (HR) of developing COPD and asthma in participants with IBD compared with them with IBD-free groups

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The one Phase 1 study (NCT02637284, 42 volunteers) posted no results

I., Kwitko, I., Roehe, D