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As regards the anthropometric measurements, the current study showed significant increase in weight z-score and height z-score with non-significant change in BMI z-score after 3 months of KD initiation (with P-values of 0.002, 0.002 and 0.06 respectively)

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The lactate leads to acidification of the environment and stabilization of activated HIF-1 in the interior region which then reinforces glycolysis in the interior region by upregulating GLUT1, LDHA, and hexokinase 2 (HK2), key proteins involved in the glycolytic pathway