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NNMT is upregulated in obesity and cancer cachexia, and NNMT knockdown in mice protects against diet-induced obesity [2]

5-Amino-1MQ is a small-molecule NNMT inhibitor

The choice between slu pp 332 and 5 amino 1mq depends on the research objectives, each compound gives unique insights into different aspects of metabolic biology

Researchers continue to investigate how NNMT inhibition affects intracellular signaling, energy utilization, and the complex biochemical pathways involved in maintaining cellular homeostasis