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Vitamin B6 (pyridoxine) serves as a necessary cofactor in the folate cycle, playing a role in neurotransmitter synthesis, such as dopamine, serotonin, GABA, noradrenaline, and melatonin

Additionally, the interaction between T cells and MHC-peptide is highly flexible, thus enabling a single T-cell receptor sequence to recognized in the region of 1 10 6 different MHC-peptide targets [82]