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Although generalized proteinuria and urinary excretion of specific tubular proteins have been used to evaluate renal tubular cell toxicity in animals and humans exposed to trichloroethylene, it should be noted that while proteinuria does result from tubular toxicity, it is not specific for trichloroethylene or tubular nephrotoxins in general (DAmico and Bazzi 2003

TB-500 has a longer plasma half-life of approximately 2-3 hours due to its larger molecular size (~4963 g/mol) and slower clearance