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Lactate: the mediator of metabolism and immunosuppression

Recently a high plasma glutamine concentration during critical illness has been suggested to be an ominous prognostic sign [2]

Xie H, Shi M, Liu Y, Cheng C, Song L, Ding Z

EC activates Nrf2, decreases HO-1 expression, and limits iron deposition, thereby suppressing ferroptosis and related gene expression (199)

The preservation of muscle architecture and age-independent regenerative capacity through localized mIgf-1 transgene expression suggests clinical strategies for the treatment of age or disease-related muscle frailty