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In addition, NAD+ serves as a substrate for numerous enzyme systems that regulate cell function

Symptoms of vitamin B12 and folate deficiency anaemia include: rapid breathing or shortness of breath headaches indigestion loss of appetite palpitations problems with your vision feeling weak or tired diarrhoea a sore or red tongue, sometimes with mouth ulcers problems with memory, understanding and judgment (cognitive changes) Some of these symptoms can also happen in people who have a vitamin B12 or folate deficiency but have not developed anaemia

Guidelines for safe and effective treatment

Parsons RB, Smith EL, Waring RH, Ramsden DB

Heres when caution is advised: Allergy concerns: People allergic to cobalt or B12 should avoid injections