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3 Potential link between gut microbiota metabolites and ITP Alterations in the gut microbiota can participate in the generation of the host immune system and in a range of inflammatory responses, and the metabolites produced by the gut microbiota, as the signaling molecules, can be seen as mediators of the interactions between the gut microbiota and their hosts

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On the other hand, fluorescent in situ hybridization revealed that MG132 treatment did not significantly affect the intracellular distribution of CFTR-F508 mRNA, although CFTR-F508 protein accumulated in an aggresome under the same conditions (Fig

Notably, L-dopa impairs homocysteine metabolism and elimination, leading to hyperhomocysteinemia and associated disorders, as confirmed by a cohort study (Mller and Kuhn 2009)

Cancer Res (1992) 52:478790

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