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Evidence-based management of herb-drug interaction in cancer chemotherapy

KD is characterized by a dietary pattern that predominates in fats, has a minimal amount of carbohydrates, and a moderate intake of protein

It aids in fat metabolism, thus helping individuals maintain their energy levels throughout the day and reduces the feeling of tiredness and lethargy

A nutritional supplement, RSV, lowers TMAO levels by reducing the gut microbial production of TMA, thus delaying CKD (Song et al., 2020)

Less commonly, berberine may cause headache or a bitter taste

16 Subsequent meta-analysis of 15 smaller RCTs with a total of 651 patients with DPN corroborated these results, emphasizing that the treatment with ALA (300-600 mg/day IV for 2-4 weeks) is safe and significantly improves neuropathic pain and nerve conduction velocity