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The synthesis of new mitochondrial components relies on a precise interaction between nuclear-encoded and mitochondrial DNA (mtDNA) mitochondrial genes, regulated by several transcription factors and signaling pathways

Intense stress or trauma and physical stressors like your environment and diet

Overall, the data obtained in this study can be translated into the possible clinical application of ternatin and its derivatives in the management of interstitial cystitis as a new efficient approach