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Epub 2022 Dec 30

For context, the recommended dietary allowance for copper in adults is approximately 0.9 mg per day, and copper clearance from tissue through standard metabolic pathways appears efficient in animal models

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4 1 C metabolism and anti-tumor therapy As discussed earlier, enzymes and metabolites involved in the synthesis and utilization of 1 C units are critical drivers of tumorigenesis and progression, either through their canonical enzymatic activities or through non-canonical functions