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Mol Aspects Med 2013

MengQYangJWangFLiCSangGLiuHet alDevelopment and external validation of nomogram to identify risk factors for CHD in T2DM in the population of Northwestern China

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Epigenomic studies have demonstrated that, in MEK inhibitorresistant cancer models, enhancer remodeling and changes in histone modifications (including elevated H3K27 acetylation) induce aberrant expression of key signaling proteins, thereby bypassing upstream inhibition and reactivating the entire ERK pathway