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Description

10.1111/j.1468-1331.2010.02966.x 9 ArgyriouA

Curiously, Cys48, Cys102, and Lys103, which were shown to be palmitoylated in vitro , are present in the hydrophobic interface of the dimer, where a lock and key motif is formed by the Tyr50 in the NH 2 -terminus of one monomer, which wedges into a hydrophobic pocket in the COOH-terminus of the other monomer (amino acids 80 to 110) [53]