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When System Xc - is inhibited, decrease in intracellular GSH synthesis leads to a significant accumulation of ROS, causing an imbalance in the cellular antioxidant system

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Interestingly, ingestion of pureed tomatoes (innately high in GABA) that contain a comparable 888 mg dose of endogenous GABA, the GABA kinetics were: t max (h) = 0.36 and the C max (ng/ml) = 184