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Associations between tear fluid biomarker concentrations and diagnostic group or amyloid PET status were assessed using a generalized linear model with a Gamma distribution and log link function, including age, sex, and APOE 4 genotype as covariates

In clinical trials (NCT01124006, NCT01158924, NCT00813813, and NCT01182337), intradiscal GDF-5 has been used to evaluate the safety, tolerability, and preliminary effectiveness in patients with early-stage lumbar disc degeneration

Assemble Nascobal (cyanocobalamin) Nasal Spray by first unscrewing the white cap from the spray solution bottle and screwing the actuator unit tightly onto the bottle