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It was first found in the segment polarity of Drosophila, where it helps to establish anterior and posterior polarities

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Not surprisingly, oki1 null mutants were lethal, however we identified a viable, and therefore weak, allele uncovering a function of the OKI1 aspartyl tRNA synthetase in meristem maintenance that could not be elucidated from null alleles

Part of the computations and data handling were enabled by resources provided by the National Academic Infrastructure for Supercomputing in Sweden (NAISS), partially funded by the Swedish Research Council through grant agreement no

507 Deletion of this gene from astrocytes decreases glutamate clearance and produces ASD-like behavioural phenotypes including aberrant locomotion and anxiety, whereas re-expression of wild type MECP2 gene in astrocytes alleviated these symptoms